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Emilin1 抗体

The 大鼠 单克隆 anti-Emilin1 antibody (Clone C11A8) (ABIN952077) specifically detects Emilin1 in WB, IHC (fro) 和 IF. The antibody is reactive with 小鼠 samples.
产品编号 ABIN952077
发货至: 中国
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Quick Overview for Emilin1 抗体 (ABIN952077)

抗原

See all Emilin1 (EMILIN1) 抗体
Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

适用

  • 26
  • 7
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
小鼠

宿主

  • 23
  • 6
  • 1
大鼠

克隆类型

  • 25
  • 5
单克隆

标记

  • 26
  • 2
  • 1
  • 1
This Emilin1 antibody is un-conjugated

应用范围

  • 22
  • 14
  • 12
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

克隆位点

C11A8
  • 特异性

    This antibody was selected for its ability to detect Murine Emilin-1.

    交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Recombinant Mouse Emilin-1

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration is 0.1-1.0 mg/mL. Centrifuge vial prior to opening.

    缓冲液

    PBS

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C for one month or at -20 °C for longer. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

    别名

    EMILIN1

    背景

    Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.Synonyms: EMI, EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1

    基因ID

    100952

    NCBI登录号

    NP_598679

    UniProt

    Q99K41
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