Endothelin 3 抗体 (C-Term)
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Quick Overview for Endothelin 3 抗体 (C-Term) (ABIN952025)
抗原
See all Endothelin 3 (EDN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 175-205, C-Term
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特异性
- This antibody recognizes Human Endothelin-3 (C-term).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- conjugated synthetic peptide between 175-205 amino acids from the C-terminal region of Human Endothelin-3. Genename: EDN3
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -80 °C for longer.
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- Endothelin 3 (EDN3)
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别名
- Endothelin-3
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背景
- The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.Synonyms: EDN3, ET-3, ET3, HSCR4, MGC15067, MGC61498, PPET3, Preproendothelin-3, WS4B
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分子量
- 25454 Da
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基因ID
- 1908
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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