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E2F2 抗体 (Middle Region)

This anti-E2F2 antibody is a 兔 多克隆 antibody detecting E2F2 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN952013
发货至: 中国

Quick Overview for E2F2 抗体 (Middle Region) (ABIN952013)

抗原

See all E2F2 抗体
E2F2 (E2F Transcription Factor 2 (E2F2))

适用

  • 61
  • 40
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  • 6
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  • 4
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  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 54
  • 7

克隆类型

  • 49
  • 12
多克隆

标记

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  • 4
  • 4
  • 2
  • 2
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  • 2
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  • 2
  • 1
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This E2F2 antibody is un-conjugated

应用范围

  • 43
  • 20
  • 13
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 265-297, Middle Region

    特异性

    This antibody recognizes Human and Mouse E2F2 (Center).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 265-297 amino acids from the Central region of Human E2F2

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    E2F2 (E2F Transcription Factor 2 (E2F2))

    别名

    E2F2

    背景

    E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq].Synonyms: E2F transcription factor 2, E2F-2, Transcription factor E2F2

    分子量

    47506 Da

    基因ID

    1870

    NCBI登录号

    NP_004082

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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