FXYD5 抗体 (Middle Region)
Quick Overview for FXYD5 抗体 (Middle Region) (ABIN952009)
抗原
See all FXYD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-100, Middle Region
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特异性
- This antibody recognizes Human Dysadherin / FXYD5 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 70-100 amino acids from the Central region of Human Dysadherin / FXYD5
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亚型
- Ig Fraction
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anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (N-Term) antibody
FXYD5 适用: 人, 小鼠, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 22-145) antibodyFXYD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (C-Term) antibodyVerified FXYD5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 54-103) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 66-115) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 108-157) antibodyFXYD5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (N-Term) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 71-100) antibodyFXYD5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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别名
- Dysadherin / FXYD5
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背景
- This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.].Synonyms: DYSAD, FXYD domain-containing ion transport regulator 5, IWU1
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基因ID
- 53827
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NCBI登录号
- NP_001158077
抗原
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