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CSDA 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects CSDA in WB 和 EIA. It exhibits reactivity toward 人 和 小鼠. It has been mentioned in 6+ publications
产品编号 ABIN951934
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CSDA 抗体 (Middle Region) (ABIN951934)

抗原

See all CSDA 抗体
CSDA (Cold Shock Domain Protein A (CSDA))

适用

  • 38
  • 26
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 34
  • 5

克隆类型

  • 36
  • 3
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CSDA antibody is un-conjugated

应用范围

  • 37
  • 16
  • 13
  • 13
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-181, Middle Region

    特异性

    This antibody recognizes Human and Mouse DNA-binding protein A (Center).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 151-181 amino acids from the Central region of Human CSDA. Genename: CSDA

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Lima, Parreira, Devuyst, Caplanusi, Nkuli, Marien, Van Der Smissen, Alves, Verroust, Christensen, Terzi, Matter, Balda, Pierreux, Courtoy: "ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 478-88, (2010) (PubMed).

    Gao, Kang, Liao, Ding, Gambotto, Watkins, Liu, Stolz, Yin: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).

    Buchert, Darido, Lagerqvist, Sedello, Cazevieille, Buchholz, Bourgaux, Pannequin, Joubert, Hollande: "The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1." in: Gastroenterology, Vol. 137, Issue 1, pp. 156-64, 164.e1-3, (2009) (PubMed).

    Sharpe Elles, Sykes, Williamson, Uhlenbeck: "A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit." in: Nucleic acids research, Vol. 37, Issue 19, pp. 6503-14, (2009) (PubMed).

    Wang, Zheng, Che, Wang, Zhao, Wu, Zeng, Pan, He: "Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells." in: Acta pharmacologica Sinica, Vol. 30, Issue 10, pp. 1436-42, (2009) (PubMed).

    Hayashi, Kajino, Umeda, Takano, Arakawa, Kudo, Hino: "Somatic mutation and SNP in the promoter of dbpA and human hepatocarcinogenesis." in: International journal of oncology, Vol. 21, Issue 4, pp. 847-50, (2002) (PubMed).

  • 抗原

    CSDA (Cold Shock Domain Protein A (CSDA))

    别名

    DNA-Binding Protein A

    背景

    CSDA binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).Synonyms: CSDA, CSDA1, Cold shock domain-containing protein A, DBPA, Single-strand DNA-binding protein NF-GMB, ZONAB

    分子量

    40090 Da

    基因ID

    8531

    NCBI登录号

    NP_001138898

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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