Cyclin T1 抗体 (Middle Region)
(1 reference)Quick Overview for Cyclin T1 抗体 (Middle Region) (ABIN951765)
抗原
See all Cyclin T1 (CCNT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 256-285, Middle Region
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特异性
- This antibody reacts to CCNT1.
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 256-285 amino acids from the Central region of human CCNT1
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亚型
- Ig Fraction
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anti-Cyclin T1 (CCNT1) (AA 375-410), (Middle Region) antibody
CCNT1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 253-281) antibodyCCNT1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19562 unconjugated
anti-Cyclin T1 (CCNT1) (N-Term) antibodyCCNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 1-726) antibodyCCNT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 466-680) antibodyCCNT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (Internal Region) antibodyVerified CCNT1 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (N-Term) antibodyCCNT1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, Pig, 豚鼠, 兔, 猴, 非洲爪蟾, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 220-320) antibodyCCNT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (N-Term) antibodyCCNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription." in: Journal of virology, Vol. 83, Issue 11, pp. 5904-17, (2009) (PubMed).
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: "Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription." in: Journal of virology, Vol. 83, Issue 11, pp. 5904-17, (2009) (PubMed).
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- Cyclin T1 (CCNT1)
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别名
- Cyclin T1
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背景
- CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.Synonyms: CCNT1, CycT1, Cyclin-T, Cyclin-T1
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分子量
- 80685 Da
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基因ID
- 904
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NCBI登录号
- NP_001231
抗原
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