Cyclin H 抗体 (C-Term)
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- 抗原 See all Cyclin H (CCNH) 抗体
- Cyclin H (CCNH)
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抗原表位
- AA 267-299, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cyclin H antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to CCNH.
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- KLH conjugated synthetic peptide between 267-299 amino acids from the C-terminal region of human CCNH
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CCNH Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS, 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Cyclin H (CCNH)
- 别名
- Cyclin H (CCNH 产品)
- 背景
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.Synonyms: CCNH, Cyclin-H, MO15-associated protein, p34, p37
- 分子量
- 37643 Da
- 基因ID
- 902
- NCBI登录号
- NP_001230
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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