CTPS2 抗体 (C-Term)
Quick Overview for CTPS2 抗体 (C-Term) (ABIN951729)
抗原
See all CTPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 449-479, C-Term
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特异性
- This antibody reacts to CTPS2.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 449-479 amino acids from the C-terminal region of human CTPS2
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CTPS2 (CTP Synthase II (CTPS2))
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别名
- CTP Synthase 2
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背景
- The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.Synonyms: CTP synthetase 2, CTPS2, UTP-ammonia ligase 2
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分子量
- 65678 Da
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基因ID
- 56474
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NCBI登录号
- NP_001137474
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途径
- Ribonucleoside Biosynthetic Process
抗原
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