CXXC1 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for CXXC1 抗体 (Middle Region) (ABIN951679)
抗原
See all CXXC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 325-354, Middle Region
-
特异性
- This antibody detects CpG-binding protein/CXXC1 (Center).
-
交叉反应 (详细)
- Species reactivity (tested):Human, Mouse
-
纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
-
免疫原
- KLH conjugated synthetic peptide from the central region (between 325-354 aa) of Human CpG-binding protein/CXXC1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- CXXC1 (CXXC Finger Protein 1 (CXXC1))
-
别名
- CpG-Binding Protein
-
背景
- Human CpG binding protein (hCGBP) contains three cysteine-rich domains, two of which exhibit homology to the plant homeodomain finger domain and the third cysteine-rich domain conforms to the CXXC motif identified in DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. A fragment of hCGBP that contains the CXXC domain binds to an oligonucleotide probe containing a single CpG site, and this complex is disrupted by distinct oligonucleotide competitors that also contain a CpG motif(s). CBGP plays an important part in embryonic viability and peri-implantation development. Native hCGBP is detected as an 88- kDa protein by Western analysis and is ubiquitously expressed. CGBP trans-activates promoters that contain CpG motifs but not promoters in which the CpG is ablated suggesting that hCGBP is a transcriptional activator that recognizes unmethylated CpG dinucleotides.Synonyms: CFP1, CGBP, CXXC-type zinc finger protein 1, CXXC1, PCCX1, PHD finger and CXXC domain-containing protein 1, PHF18
-
基因ID
- 30827
-
NCBI登录号
- NP_001095124
-
途径
- ER-Nucleus Signaling
抗原
-