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CXXC1 抗体 (Middle Region)

This anti-CXXC1 antibody is a 兔 多克隆 antibody detecting CXXC1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN951679
发货至: 中国

Quick Overview for CXXC1 抗体 (Middle Region) (ABIN951679)

抗原

See all CXXC1 抗体
CXXC1 (CXXC Finger Protein 1 (CXXC1))

适用

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人, 小鼠

宿主

  • 38

克隆类型

  • 38
多克隆

标记

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This CXXC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 325-354, Middle Region

    特异性

    This antibody detects CpG-binding protein/CXXC1 (Center).

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse

    纯化方法

    Purified through a protein A column; followed by peptide affinity purification.

    免疫原

    KLH conjugated synthetic peptide from the central region (between 325-354 aa) of Human CpG-binding protein/CXXC1.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CXXC1 (CXXC Finger Protein 1 (CXXC1))

    别名

    CpG-Binding Protein

    背景

    Human CpG binding protein (hCGBP) contains three cysteine-rich domains, two of which exhibit homology to the plant homeodomain finger domain and the third cysteine-rich domain conforms to the CXXC motif identified in DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. A fragment of hCGBP that contains the CXXC domain binds to an oligonucleotide probe containing a single CpG site, and this complex is disrupted by distinct oligonucleotide competitors that also contain a CpG motif(s). CBGP plays an important part in embryonic viability and peri-implantation development. Native hCGBP is detected as an 88- kDa protein by Western analysis and is ubiquitously expressed. CGBP trans-activates promoters that contain CpG motifs but not promoters in which the CpG is ablated suggesting that hCGBP is a transcriptional activator that recognizes unmethylated CpG dinucleotides.Synonyms: CFP1, CGBP, CXXC-type zinc finger protein 1, CXXC1, PCCX1, PHD finger and CXXC domain-containing protein 1, PHF18

    基因ID

    30827

    NCBI登录号

    NP_001095124

    途径

    ER-Nucleus Signaling
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