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COX10 抗体 (C-Term)

This anti-COX10 antibody is a 兔 多克隆 antibody detecting COX10 in WB, FACS, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN951674
发货至: 中国

Quick Overview for COX10 抗体 (C-Term) (ABIN951674)

抗原

See all COX10 抗体
COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

适用

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宿主

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克隆类型

  • 34
多克隆

标记

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This COX10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 386-414, C-Term

    特异性

    This antibody reacts to COX10.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human COX1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

    别名

    COX10

    背景

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.Synonyms: COX-10, Heme O synthase, mitochondrial Protoheme IX farnesyltransferase

    分子量

    48910 Da

    基因ID

    1352

    NCBI登录号

    NP_001294
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