Complex IV Subunit VIb (AA 58-86), (C-Term) 抗体
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Quick Overview for Complex IV Subunit VIb (AA 58-86), (C-Term) 抗体 (ABIN951654)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- AA 58-86, C-Term
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特异性
- This antibody reacts to COX6B1.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 58-86 amino acids from the C-terminal region of human COX6B1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Complex IV Subunit VIb
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背景
- Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.Synonyms: COX6B, COX6B1, Cytochrome c oxidase subunit 6B1, Mitochondria Complex IV
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分子量
- 10192 Da
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基因ID
- 1340
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NCBI登录号
- NP_001854
抗原
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