Coilin 抗体 (Middle Region)
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Quick Overview for Coilin 抗体 (Middle Region) (ABIN951619)
抗原
See all Coilin (COIL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 156-186, Middle Region
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特异性
- This antibody reacts to COIL.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 156-186 amino acids from the Central region of human COIL
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Coilin (COIL)
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别名
- Coilin
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背景
- The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.Synonyms: CLN80, COIL, p80
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分子量
- 62608 Da
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基因ID
- 8161
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NCBI登录号
- NP_004636
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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