Factor XI 抗体 (Middle Region)
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Quick Overview for Factor XI 抗体 (Middle Region) (ABIN951607)
抗原
See all Factor XI (F11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 288-315, Middle Region
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特异性
- This antibody recognizes Human Coagulation factor XI (F11) (Center).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 288-315 amino acids from the Central region of human F11.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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背景
- This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].Synonyms: FX1, PTA, Plasma thromboplastin antecedent
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分子量
- 70109 Da
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基因ID
- 2160
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NCBI登录号
- NP_000119
抗原
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