Coagulation Factor IX 抗体
Quick Overview for Coagulation Factor IX 抗体 (ABIN951594)
抗原
See all Coagulation Factor IX (F9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
 - Recognises Factor IX
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纯化方法
 - Protein G Chromatography
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免疫原
 - Full length native protein (purified) (Human).
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亚型
 - IgG1
 
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应用备注
 - Optimal working dilution should be determined by the investigator.
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限制
 - 仅限研究用
 
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浓度
 - 3.5 mg/mL
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缓冲液
 - 0.05 M Sodium Phosphate, 0.5 M NaCl, 1 mM EDTA, pH 6.6
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注意事项
 - Avoid repeated freezing and thawing.
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储存条件
 - -80 °C
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储存方法
 - Store at -70 °C.
 
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- Coagulation Factor IX (F9)
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背景
 - Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.Synonyms: Christmas factor, PTC, Plasma thromboplastin component
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基因ID
 - 2158
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NCBI登录号
 - NP_000124
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UniProt
 - P00740
 
抗原
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