Claudin 6 抗体 (Middle Region)
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北京 101111
Quick Overview for Claudin 6 抗体 (Middle Region) (ABIN951551)
抗原
See all Claudin 6 (CLDN6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-163, Middle Region
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特异性
- This antibody recognizes Human CLDN6. Other species not tested.
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 133-163 amino acids from the Central region of human CLDN6
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Claudin 6 (CLDN6)
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别名
- Claudin-6 / CLDN6
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背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.Synonyms: PRO1488, Skullin, Skullin 2, UNQ757
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分子量
- 23292 Da
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基因ID
- 9074
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NCBI登录号
- NP_067018
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途径
- Hepatitis C
抗原
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