CD8B 抗体 (FITC)
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Quick Overview for CD8B 抗体 (FITC) (ABIN951409)
抗原
See all CD8B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This monoclonal antibody reacts with the beta chain of the CD8 differentiation antigen. The 3.4.1 antibody also blocks both activation in an allogenic response and cell mediated cytotoxicity by CD8 T cells.
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交叉反应 （详细）
- Species reactivity (tested):Rat.
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纯化方法
- Protein G Chromatography of Ascites fluid.
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免疫原
- Rat/mouse T cell hybrids expressing CD8. Remarks: Donor: BALB/c mouse spleen cells. Fusion Partner: X63 Ag.653 myeloma cell line.
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亚型
- IgG1
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anti-CD8b Molecule (CD8B) (AA 51-150) antibody
CD8B 适用: 人 WB, ELISA, ICC, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibodyCD8B 适用: 大鼠 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 341 unconjugated
anti-CD8b Molecule (CD8B) antibody (FITC)CD8B 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 341 FITC
anti-CD8b Molecule (CD8B) antibody (PE)CD8B 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 341 PE
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibody (FITC)CD8B 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal H35-17-2 FITC
anti-CD8b Molecule (CD8B) (AA 1-243) antibodyCD8B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibodyCD8B 适用: 大鼠 FACS, WB, IP, Func, IHC (fro) 宿主: 小鼠 Monoclonal 341 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD8B (CD8b Molecule (CD8B))
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别名
- CD8 beta
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背景
- CD8b is expressed on most thymocytes and mature T cytotoxic/suppressor cells (MHC class I restricted). While the CD8a and CD8b form a heterodimer on the surface of thymocytes and thymus-dependent T cytotoxic/suppressor cells, the majority of NK cells, many CD8 T cells from athymic rats, many activated CD4 T cells, and intestinal epithelium lymphocytes (IEL) express CD8a without CD8b. This suggests that expression of the CD8 heterodimer (a/b) is more dependant on intrathymic T cell maturation than that of the homodimer (a/a). The thymus dependence of CD8a/b T cells may be due to a requirement for thymic selection on self MHC class I antigens.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain
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基因ID
- 24931
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NCBI登录号
- NP_113727
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UniProt
- P05541
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途径
- TCR Signaling
抗原
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