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CD8B 抗体 (Biotin)

This anti-CD8B antibody is a 大鼠 单克隆 antibody detecting CD8B in FACS. Suitable for 小鼠.
产品编号 ABIN951402
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD8B 抗体 (Biotin) (ABIN951402)

抗原

See all CD8B 抗体
CD8B (CD8b Molecule (CD8B))

适用

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小鼠

宿主

  • 72
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大鼠

克隆类型

  • 88
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单克隆

标记

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This CD8B antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

CT-CD8b
  • 特异性

    This anti-mouse CD8β Chain monoclonal antibody reacts with the mouse CD8 chain. The CD8 β Chain is also named Ly-3. The CD8 chain associates with the CD8 chain to form the CD8 / heterodimer on MHC class I restricted T-cells (cytotoxic T cells) and most thymocytes1. Since a small subset of T cells (IEL cells) express CD8 / homodimers rather than CD8 / heterodimers, investigators should use an antibody directed against the CD8 chain (CL168B, clone CT-CD8a) to definitively label mouse CD8 cells.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. Should this product contain a precipitate we recommend microcentrifugation before use.
  • 抗原

    CD8B (CD8b Molecule (CD8B))

    别名

    CD8 beta

    背景

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain

    基因ID

    12526

    NCBI登录号

    NP_033988

    UniProt

    P10300

    途径

    TCR Signaling
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