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CD8 抗体 (Biotin)

This anti-CD8 antibody is a 大鼠 单克隆 antibody detecting CD8 in FACS. Suitable for 小鼠.
产品编号 ABIN951387
发货至: 中国

Quick Overview for CD8 抗体 (Biotin) (ABIN951387)

抗原

See all CD8 抗体
CD8

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD8 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

YTS169-4
  • 特异性

    This anti-mouse CD8a (Ly 2) monoclonal antibody reacts with a protein of approximately 30 kDa found on mouse thymocytes and mouse cytotoxic/ suppressor T cells. It does not bind to mouse helper/inducer T cells. It binds to T lymphocytes from all mouse strains regardless of phenotypic expression (i.e. reacts with T lymphocytes from mouse strains expressing the Ly 2.1 or Ly 2.2 phenotype). It can be used to investigate the role of T cells in models for infectious disease, autoimmunity, transplantation tolerance and fundamental aspects of immunology.

    纯化方法

    Protein G Chromatography

    免疫原

    Murine thymocytes Donor: (LOU X DA) F1 rats Fusion Partner: Myeloma Y3/Ag 1.2.3

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原

    CD8

    别名

    CD8

    背景

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

    基因ID

    12525

    NCBI登录号

    NP_001074579

    UniProt

    P01731
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