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CD8 抗体 (Biotin)

CD8 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal YTS169-4 Biotin
产品编号 ABIN951387
发货至: 中国
  • 抗原 See all CD8 抗体
    CD8
    适用
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    小鼠
    宿主
    • 226
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    大鼠
    克隆类型
    • 277
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    单克隆
    标记
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    This CD8 antibody is conjugated to Biotin
    应用范围
    • 276
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    Flow Cytometry (FACS)
    特异性
    This anti-mouse CD8a (Ly 2) monoclonal antibody reacts with a protein of approximately 30 kDa found on mouse thymocytes and mouse cytotoxic/ suppressor T cells. It does not bind to mouse helper/inducer T cells. It binds to T lymphocytes from all mouse strains regardless of phenotypic expression (i.e. reacts with T lymphocytes from mouse strains expressing the Ly 2.1 or Ly 2.2 phenotype). It can be used to investigate the role of T cells in models for infectious disease, autoimmunity, transplantation tolerance and fundamental aspects of immunology.
    纯化方法
    Protein G Chromatography
    免疫原
    Murine thymocytes Donor: (LOU X DA) F1 rats Fusion Partner: Myeloma Y3/Ag 1.2.3
    克隆位点
    YTS169-4
    亚型
    IgG2b
    Top Product
    Discover our top product CD8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原
    CD8
    别名
    CD8 (CD8 产品)
    背景
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
    基因ID
    12525
    NCBI登录号
    NP_001074579
    UniProt
    P01731
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