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CD63 抗体 (Biotin)

CD63 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-259 Biotin
产品编号 ABIN951367
发货至: 中国
  • 抗原 See all CD63 抗体
    CD63
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD63 antibody is conjugated to Biotin
    应用范围
    • 90
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    Flow Cytometry (FACS)
    特异性
    This antibody MEM-259 reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    克隆位点
    MEM-259
    亚型
    IgG1
    Top Product
    Discover our top product CD63 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate Buffered Saline (PBS), pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD63
    别名
    CD63 (CD63 产品)
    背景
    CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.Synonyms: Granulophysin, ME491, MLA1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, TSPAN30, Tetraspanin-30
    基因ID
    967
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