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CD247 抗体

CD247 适用: 人, 小鼠 WB, FACS, IF, EIA 宿主: 仓鼠 Monoclonal H146-968 unconjugated
产品编号 ABIN951241
发货至: 中国
  • 抗原 See all CD247 抗体
    CD247 (CD247 Molecule (CD247))
    适用
    • 93
    • 41
    • 18
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 75
    • 16
    • 5
    • 1
    仓鼠
    克隆类型
    • 73
    • 24
    单克隆
    标记
    • 55
    • 9
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CD247 antibody is un-conjugated
    应用范围
    • 72
    • 53
    • 34
    • 14
    • 10
    • 10
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects the zeta subunit of the T cell receptor (TCR).
    纯化方法
    Protein G Affinity Chromatography.
    克隆位点
    H146-968
    亚型
    IgG
    Top Product
    Discover our top product CD247 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD247 (CD247 Molecule (CD247))
    别名
    CD247 / CD3Z (CD247 产品)
    别名
    CD3-ZETA antibody, CD3H antibody, CD3Q antibody, CD3Z antibody, T3Z antibody, TCRZ antibody, 4930549J05Rik antibody, A430104F18Rik antibody, AW552088 antibody, Cd3 antibody, Cd3-eta antibody, Cd3-zeta antibody, Cd3h antibody, Cd3z antibody, Cd3zeta antibody, T3z antibody, Tcrk antibody, Tcrz antibody, LOC100136514 antibody, LOC100136549 antibody, LOC100305023 antibody, CD247 antibody, TCRzeta antibody, CD247 molecule antibody, CD247 antigen antibody, CD3zeta-2 antibody, CD3zeta-1 antibody, Cd247 molecule antibody, CD247 antibody, Cd247 antibody, cd3z antibody, cd247 antibody
    背景
    The TCR complex consists of a ligand specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma, delta, eta and zeta subunits. This complex regulates assembly and expression of the receptor and is thought to be responsible for transmembrane transduction of signals after binding to TCRαβ. Studies have suggested that the CD3z subunit (also know as CD247) plays an important role in two distinct cellular compartments. In the cytoplasm, it may function to regulate Ag receptor expression and in the plasma membrane it may be required for optimal signaling by the physiologic ligand Ag/MHC. The CD3z subunit is also associated with the CD16 IgG Fc receptor on NK cells.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ
    基因ID
    12503
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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