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CD247 抗体 (AA 151-164) (FITC)

CD247 适用: 人, 小鼠 FACS, IF 宿主: 仓鼠 Monoclonal H146-968 FITC
产品编号 ABIN951240
发货至: 中国
  • 抗原 See all CD247 抗体
    CD247 (CD247 Molecule (CD247))
    抗原表位
    • 13
    • 13
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-164
    适用
    • 88
    • 40
    • 17
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 72
    • 14
    • 5
    • 1
    仓鼠
    克隆类型
    • 71
    • 21
    单克隆
    标记
    • 52
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CD247 antibody is conjugated to FITC
    应用范围
    • 71
    • 50
    • 30
    • 14
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    The antibody reacts with CD3 zeta chain (CD247), which is a component of TCR/CD3 complex expressed on T cells.
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    产品特性
    Synonyms: T3Z, TCRZ, CD3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3zeta chain
    免疫原
    Synthetic peptide corresponding to amino acids 151-164 of Mouse CD3 zeta
    克隆位点
    H146-968
    亚型
    IgG
    Top Product
    Discover our top product CD247 Primary Antibody
  • 应用备注
    Flow Cytometry: 2 μg/mL (starting point).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD247 (CD247 Molecule (CD247))
    别名
    CD247 / CD3Z (CD247 产品)
    别名
    CD3-ZETA antibody, CD3H antibody, CD3Q antibody, CD3Z antibody, T3Z antibody, TCRZ antibody, 4930549J05Rik antibody, A430104F18Rik antibody, AW552088 antibody, Cd3 antibody, Cd3-eta antibody, Cd3-zeta antibody, Cd3h antibody, Cd3z antibody, Cd3zeta antibody, T3z antibody, Tcrk antibody, Tcrz antibody, LOC100136514 antibody, LOC100136549 antibody, LOC100305023 antibody, CD247 antibody, TCRzeta antibody, CD247 molecule antibody, CD247 antigen antibody, CD3zeta-2 antibody, CD3zeta-1 antibody, Cd247 molecule antibody, CD247 antibody, Cd247 antibody, cd3z antibody, cd247 antibody
    背景
    CD3 complex is crucial in transducing antigen-recognition signals into the cytopasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta (CD247). These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ
    基因ID
    12503
    UniProt
    P24161
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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