LY75/DEC-205 抗体 (PE)
Quick Overview for LY75/DEC-205 抗体 (PE) (ABIN951226)
抗原
See all LY75/DEC-205 (LY75) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects CD205.
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交叉反应 (详细)
- Species reactivity (tested):Human
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免疫原
- Recombinant Fc-tagged human CD205
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE! This product is photosensitive and should be protected from light.
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储存条件
- 4 °C
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- LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
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别名
- CD205 / DEC-205
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背景
- CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6
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基因ID
- 100526664
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NCBI登录号
- NP_001185688
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UniProt
- O60449
抗原
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