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LY75/DEC-205 抗体 (PE)

LY75 适用: 人 FACS 宿主: 小鼠 Monoclonal HD30 PE
产品编号 ABIN951226
发货至: 中国
  • 抗原 See all LY75/DEC-205 (LY75) 抗体
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    适用
    • 45
    • 27
    • 9
    • 9
    • 2
    宿主
    • 36
    • 24
    • 7
    • 1
    • 1
    小鼠
    克隆类型
    • 39
    • 29
    • 1
    单克隆
    标记
    • 31
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LY75/DEC-205 antibody is conjugated to PE
    应用范围
    • 27
    • 21
    • 18
    • 16
    • 13
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody detects CD205.
    交叉反应 (详细)
    Species reactivity (tested):Human
    免疫原
    Recombinant Fc-tagged human CD205
    克隆位点
    HD30
    亚型
    IgG1
    Top Product
    Discover our top product LY75 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE! This product is photosensitive and should be protected from light.
    储存条件
    4 °C
  • 抗原
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    别名
    CD205 / DEC-205 (LY75 产品)
    背景
    CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6
    基因ID
    100526664
    NCBI登录号
    NP_001185688
    UniProt
    O60449
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