The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.Synonyms: CD172 antigen-like family member B, SIRP gamma, SIRP-b2, SIRP-beta-2, SIRPB2, Signal-regulatory protein beta-2, Signal-regulatory protein gamma