CARM1 抗体 (Middle Region)
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北京 101111
Quick Overview for CARM1 抗体 (Middle Region) (ABIN951046)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to PRMT4.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide selected from the Central region of human PRMT4
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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别名
- CARM1 / PRMT4
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背景
- Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).Synonyms: Coactivator-associated arginine methyltransferase 1, Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 4
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分子量
- 65854 Da
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基因ID
- 10498
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NCBI登录号
- NP_954592
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
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