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BCL6 抗体 (C-Term)

The 兔 多克隆 anti-BCL6 antibody is suitable to detect BCL6 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN950636
发货至: 中国
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Quick Overview for BCL6 抗体 (C-Term) (ABIN950636)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 675-704, C-Term

    特异性

    This antibody reacts to Bcl-6.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 675-704 amino acids from the C-terminal region of human BCL6

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    Bcl-6

    背景

    The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.Synonyms: B-cell lymphoma 6 protein, BCL-5, BCL5, BCL6, LAZ-3, LAZ3, ZBTB27, ZNF51, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51

    基因ID

    604

    NCBI登录号

    NP_001124317

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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