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BCL10 抗体 (N-Term)

BCL10 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN950621
发货至: 中国
  • 抗原 See all BCL10 抗体
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    抗原表位
    • 17
    • 15
    • 9
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-55, N-Term
    适用
    • 104
    • 36
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 75
    • 29
    克隆类型
    • 62
    • 43
    多克隆
    标记
    • 48
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL10 antibody is un-conjugated
    应用范围
    • 79
    • 33
    • 32
    • 31
    • 29
    • 19
    • 13
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reats to Bcl-10.
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human BCL10
    亚型
    Ig Fraction
    Top Product
    Discover our top product BCL10 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    别名
    Bcl-10 (BCL10 产品)
    别名
    CARMEN antibody, CIPER antibody, CLAP antibody, c-E10 antibody, mE10 antibody, BCL10 antibody, AI132454 antibody, BCL-10 antibody, C81403 antibody, ME10 antibody, cE10 antibody, bcl10 antibody, B-cell CLL/lymphoma 10 antibody, B-cell lymphoma/leukemia 10-like antibody, B cell leukemia/lymphoma 10 antibody, B-cell lymphoma/leukemia 10 antibody, BCL10 antibody, Bcl10 antibody, bcl10 antibody, LOC100223183 antibody
    背景
    This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.Synonyms: B-cell CLL/lymphoma 10, BCL10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, hCLAP, mE10
    基因ID
    8915
    NCBI登录号
    NP_003912
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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