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KIDINS220 抗体 (C-Term)

This anti-KIDINS220 antibody is a 兔 多克隆 antibody detecting KIDINS220 in WB 和 EIA. Suitable for 人.
产品编号 ABIN950511
发货至: 中国
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Quick Overview for KIDINS220 抗体 (C-Term) (ABIN950511)

抗原

See all KIDINS220 抗体
KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

适用

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宿主

  • 36
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克隆类型

  • 36
  • 9
多克隆

标记

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This KIDINS220 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 9
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    AA 1517-1547, C-Term

    特异性

    This antibody recognizes Human ARMS / KIDINS220 (C-term).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 1517-1547 amino acids from the C-terminal region of Human ARMS / KIDINS220

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

    别名

    ARMS / KIDINS220

    背景

    KIDINS220 promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.Synonyms: Ankyrin repeat-rich membrane spanning protein, KIAA1250, Kinase D-interacting substrate of 220 kDa

    分子量

    196542 Da

    基因ID

    57498

    NCBI登录号

    NP_065789
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