KIDINS220 抗体 (C-Term)
Quick Overview for KIDINS220 抗体 (C-Term) (ABIN950511)
抗原
See all KIDINS220 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1517-1547, C-Term
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特异性
- This antibody recognizes Human ARMS / KIDINS220 (C-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 1517-1547 amino acids from the C-terminal region of Human ARMS / KIDINS220
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亚型
- Ig Fraction
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anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (Internal Region) antibody
KIDINS220 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (C-Term) antibodyKIDINS220 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (pSer918) antibodyKIDINS220 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1335-1348), (Intracellular) antibodyKIDINS220 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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别名
- ARMS / KIDINS220
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背景
- KIDINS220 promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.Synonyms: Ankyrin repeat-rich membrane spanning protein, KIAA1250, Kinase D-interacting substrate of 220 kDa
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分子量
- 196542 Da
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基因ID
- 57498
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NCBI登录号
- NP_065789
抗原
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