ARHGAP10 抗体 (Middle Region)
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Quick Overview for ARHGAP10 抗体 (Middle Region) (ABIN950486)
抗原
See all ARHGAP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-267, Middle Region
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特异性
- This antibody reacts to ARHGAP10.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 240-267 amino acids from the Central region of human ARHGAP10
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))
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别名
- ARHGAP10 / GRAF2
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背景
- GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).Synonyms: GTPase regulator associated with focal adhesion kinase 2, Graf-related protein 2, Rho GTPase-activating protein 10, Rho-type GTPase-activating protein 10
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基因ID
- 79658
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NCBI登录号
- NP_078881
抗原
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