ANGPTL4 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for ANGPTL4 抗体 (Middle Region) (ABIN950414)
抗原
See all ANGPTL4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 145-175, Middle Region
-
特异性
- This antibody reacts to ANGPTL4.
-
交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
-
纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
-
免疫原
- KLH conjugated synthetic peptide between 145~175 amino acids from the Center region of human ANGPTL4
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS containing 0.09 % (W/V) sodium azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
-
别名
- ANGPTL4 / FIAF
-
背景
- ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.Synonyms: ARP4, Angiopoietin-like 4, Angiopoietin-related protein 4, Fasting-induced adipose factor, HFARP, Hepatic fibrinogen/angiopoietin-related protein, PGAR
-
基因ID
- 51129
-
NCBI登录号
- NP_001034756
-
途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
-