Neuron-specific enolase 1 (NSE-P1, ENO1, Enolase 1, 2-Phospho-D-Glycerate Hydrolase, alpha enolase, alpha/gamma) is an 80 kD protein and one of the five isozymes of enolase, a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. Enolase is thought to serve as a growth factor in neurons and is released into the central nervous system when neural tissue is injured. Measurement of NSE levels in patients with neuroblastoma and small lung cancer can give an indication as to the extent of the disease. NSE-P1 is one of three different enolase isozymes found in the Human brain.Synonyms: 2-phospho-D-glycerate hydro-lyase, C-myc promoter-binding protein, ENO1L1 Non-neural enolase, Enolase 1, MBP-1, MBPB1, MPB-1, MPB1, NNE, Phosphopyruvate hydratase, Plasminogen-binding protein