ALOXE3 抗体 (Middle Region)
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北京 101111
Quick Overview for ALOXE3 抗体 (Middle Region) (ABIN950356)
抗原
See all ALOXE3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-260, Middle Region
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特异性
- This antibody reacts to ALOXE3.
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交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 230-260 amino acids from the Central region of human ALOXE3
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
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别名
- ALOXE3
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背景
- ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.Synonyms: Epidermis-type lipoxygenase 3, e-LOX-3, eLOX3
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基因ID
- 59344
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NCBI登录号
- NP_001159432
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途径
- Cell-Cell Junction Organization
抗原
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