ADAM9 抗体 (Extracellular Domain)
Quick Overview for ADAM9 抗体 (Extracellular Domain) (ABIN950269)
抗原
See all ADAM9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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纯化方法
- Protein A/G Affinity Chromatography
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免疫原
- Purified Recombinant ADAM9 extracellular domain.
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亚型
- IgG2
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anti-ADAM Metallopeptidase Domain 9 (ADAM9) (AA 475-685) antibody
ADAM9 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) (AA 36-135) antibodyADAM9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) (AA 475-685) antibodyADAM9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) (AA 704-733), (C-Term) antibodyADAM9 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17777 unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) (AA 35-64), (N-Term) antibodyADAM9 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB17776 unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) antibodyResearch Grade ADAM9 适用: 人 ELISA, FACS 宿主: Humanized Monoclonal unconjugated Recombinant Antibody
anti-ADAM Metallopeptidase Domain 9 (ADAM9) antibodyADAM9 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) (AA 396-445) antibodyADAM9 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) antibodyADAM9 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal unconjugated
anti-ADAM Metallopeptidase Domain 9 (ADAM9) antibodyADAM9 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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缓冲液
- 0.2 μm filtered PBS solution, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.
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有效期
- 6 months
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- ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))
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别名
- ADAM9 / MDC9
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背景
- ADAM9, also known as MDC9 or meltrin γ, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. Like other membrane-anchored ADAMs, ADAM9 consists of a pro domain with a cysteine switch and furin cleavage sequence, a catalytic domain with the zinc-binding site and Metturn expected for reprolysins, a disintegrin like domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and the cytoplasmic domain. ADAM9 is able to cleave peptides corresponding to cleavage sites of tumor necrosis factorα (TNFα), the p75 TNF receptor, the β-amyloid protein precursor, and the c-kit ligand1, implying that it may participate in shedding of these membrane proteins. In fact, ADAM9 has been shown to shed membrane-anchored heparin-binding EGF-like growth factor. In addition, it also cleaves oxidized insulin B-chain and fibronectin. Besides its catalytic activity, ADAM9 functions as an adhesion molelcule through binding of its disintegrin domain to integrins such as αvβ5 and α6β1. The cytoplasmic domain of ADAM9 interacts with Src homology 3 (SH3)containing proteins and protein kinase C, and may mediate different signaling pathways. ADAM9 is widely expressed in tissues.Synonyms: Cellular disintegrin-related protein, Disintegrin and metalloproteinase domain-containing protein 9, KIAA0021, MCMP, MLTNG, Meltrin gamma, Metalloprotease/disintegrin/cysteine-rich protein 9, Myeloma cell metalloproteinase
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基因ID
- 10090
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UniProt
- Q61072
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途径
- Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome
抗原
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