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Kinesin 抗体 (AA 331-906)

This anti-Kinesin antibody is a 兔 多克隆 antibody detecting Kinesin in WB 和 ICC. Suitable for 人, 小鼠 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN94498
发货至: 中国

Quick Overview for Kinesin 抗体 (AA 331-906) (ABIN94498)

抗原

Kinesin

适用

  • 21
  • 19
  • 3
  • 3
  • 2
人, 小鼠, Pig

宿主

  • 19
  • 5

克隆类型

  • 19
  • 5
多克隆

标记

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Kinesin antibody is un-conjugated

应用范围

  • 14
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
    • 2
    • 1
    • 1
    • 1
    AA 331-906

    原理

    Anti-Kinesin Purified

    特异性

    The polyclonal antibody detects total level of endogenous kinesin protein (intracellular antigen).

    交叉反应 (详细)

    Human, Mouse, Porcine, Other not tested

    纯化方法

    Purified by ligand affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    stalk domain of human kinesin (aa 331-906) expressed in E. coli (FKHC3)
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Malcová-Janatová, Richterová, Dráber, Hasek: "Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." in: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).

  • 抗原

    Kinesin

    背景

    Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.,KIN
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