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B-Cell Linker 抗体 (AA 171-356)

BLNK 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN94495
发货至: 中国
  • 抗原 See all B-Cell Linker (BLNK) 抗体
    B-Cell Linker (BLNK)
    抗原表位
    • 24
    • 22
    • 17
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-356
    适用
    • 103
    • 67
    • 38
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 112
    • 8
    • 1
    克隆类型
    • 107
    • 14
    多克隆
    标记
    • 51
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    This B-Cell Linker antibody is un-conjugated
    应用范围
    • 108
    • 52
    • 36
    • 26
    • 26
    • 19
    • 18
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The polyclonal antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).
    交叉反应 (详细)
    Mouse
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    A fusion protein representing amino acids 171-356 of human BLNK.
    Top Product
    Discover our top product BLNK Primary Antibody
  • 应用备注
    Western blotting: Reducing conditions.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    B-Cell Linker (BLNK)
    别名
    SLP65 / BLNK (BLNK 产品)
    别名
    BLNK antibody, blnk antibody, MGC147045 antibody, BASH antibody, Bca antibody, Ly-57 antibody, Ly57 antibody, Lyw-57 antibody, SLP-65 antibody, AGM4 antibody, BLNK-S antibody, LY57 antibody, SLP65 antibody, bca antibody, B-cell linker antibody, B cell linker antibody, BLNK antibody, blnk antibody, Blnk antibody
    背景
    B cell linkerprovided,SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa, B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins, thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.,SLP65, BASH, Ly57
    基因ID
    29760
    UniProt
    Q8WV28
    途径
    BCR Signaling
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