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B-Cell Linker 抗体 (AA 171-356)

This 兔 多克隆 antibody specifically detects B-Cell Linker in WB. It exhibits reactivity toward 小鼠.
产品编号 ABIN94495
发货至: 中国
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Quick Overview for B-Cell Linker 抗体 (AA 171-356) (ABIN94495)

抗原

See all B-Cell Linker (BLNK) 抗体
B-Cell Linker (BLNK)

适用

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  • 84
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  • 2
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  • 1
小鼠

宿主

  • 124
  • 8
  • 1

克隆类型

  • 113
  • 20
多克隆

标记

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  • 2
  • 2
  • 2
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This B-Cell Linker antibody is un-conjugated

应用范围

  • 120
  • 52
  • 36
  • 28
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  • 20
  • 19
  • 9
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  • 6
  • 3
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 25
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    • 15
    • 9
    • 5
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    • 1
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    • 1
    AA 171-356

    原理

    Anti-Ms Blnk Purified

    交叉反应 (详细)

    Mouse

    产品特性

    The polyclonal antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    A fusion protein representing amino acids 171-356 of human BLNK.
  • 应用备注

    Western blotting: Reducing conditions.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    B-Cell Linker (BLNK)

    别名

    Blnk

    背景

    B cell linkerprovided,SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa, B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins, thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.,SLP65, BASH, Ly57

    基因ID

    29760

    UniProt

    Q8WV28

    途径

    BCR Signaling
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