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HLA-DP/DR 抗体

HLA-DP/DR 适用: 人, Pig FACS, IP, WB, IHC (p) 宿主: 小鼠 Monoclonal HL-38 unconjugated
产品编号 ABIN94346
发货至: 中国
  • 抗原 See all HLA-DP/DR products
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    适用
    人, Pig
    宿主
    • 15
    小鼠
    克隆类型
    • 15
    单克隆
    标记
    • 4
    • 4
    • 3
    • 2
    • 2
    This HLA-DP/DR antibody is un-conjugated
    应用范围
    • 15
    • 7
    • 7
    • 4
    • 3
    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Anti-HLA-DR/DP Purified
    特异性
    The antibody HL-38 recognizes an extracellular common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    交叉反应 (详细)
    Human, Porcine
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Raji Burkitt's lymphoma cell line
    克隆位点
    HL-38
    亚型
    IgG2a
  • 应用备注
    Western blotting: Recommended dilution: 1 μg/mL
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • 抗原
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    别名
    HLA-DR/DP (HLA-DP/DR 产品)
    背景
    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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