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HLA-DP/DR 抗体

This anti-HLA-DP/DR antibody is a 小鼠 单克隆 antibody detecting HLA-DP/DR in FACS, IP, WB 和 IHC (p). Suitable for 人 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN94346
发货至: 中国

Quick Overview for HLA-DP/DR 抗体 (ABIN94346)

抗原

HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

适用

人, Pig

宿主

  • 15
小鼠

克隆类型

  • 15
单克隆

标记

  • 4
  • 4
  • 3
  • 2
  • 2
This HLA-DP/DR antibody is un-conjugated

应用范围

  • 15
  • 7
  • 7
  • 4
  • 3
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

HL-38
  • 原理

    Anti-HLA-DR/DP Purified

    特异性

    The antibody HL-38 recognizes an extracellular common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

    交叉反应 (详细)

    Human, Porcine

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Raji Burkitt's lymphoma cell line

    亚型

    IgG2a
  • 应用备注

    Western blotting: Recommended dilution: 1 μg/mL
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • 抗原

    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

    别名

    HLA-DR/DP

    背景

    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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