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HLA-DP/DR 抗体

HLA-DP/DR 适用: 人 FACS, IP, WB, IHC (p) 宿主: 小鼠 Monoclonal MEM-136 unconjugated
产品编号 ABIN94344
发货至: 中国
  • 抗原 See all HLA-DP/DR products
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    适用
    • 15
    • 5
    宿主
    • 15
    小鼠
    克隆类型
    • 15
    单克隆
    标记
    • 4
    • 4
    • 3
    • 2
    • 2
    This HLA-DP/DR antibody is un-conjugated
    应用范围
    • 15
    • 7
    • 7
    • 4
    • 3
    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Anti-HLA-DR/DP Purified
    特异性
    The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    PHA-activated peripheral blood lymphocytes.
    克隆位点
    MEM-136
    亚型
    IgG1
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Western blotting: Recommended dilution: 1 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." in: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

  • 抗原
    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))
    别名
    HLA-DR/DP (HLA-DP/DR 产品)
    背景
    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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