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CD97 抗体 (FITC)

There is 1 publication for this product available. The 小鼠 单克隆 anti-CD97 antibody is suitable to detect CD97 in samples from 人. It has been validated for FACS.
产品编号 ABIN94253
发货至: 中国
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Quick Overview for CD97 抗体 (FITC) (ABIN94253)

抗原

See all CD97 抗体
CD97

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD97 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-180
  • 原理

    Anti-Hu CD97 FITC

    特异性

    The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    PHA-activated peripheral blood cells

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 溶解方式

    No reconstitution is necessary.

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Wobus, Vogel, Schmücking, Hamann, Aust: "N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding." in: International journal of cancer. Journal international du cancer, Vol. 112, Issue 5, pp. 815-22, (2004) (PubMed).

  • 抗原

    CD97

    别名

    CD97

    背景

    Adhesion G protein-coupled receptor E5,CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.,TM7LN1, ADGRE5

    基因ID

    976

    UniProt

    P48960
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