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CD9 抗体

This anti-CD9 antibody is a 小鼠 单克隆 antibody detecting CD9 in FACS, WB, IHC (p) 和 MS. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN94244
发货至: 中国

Quick Overview for CD9 抗体 (ABIN94244)

抗原

See all CD9 抗体
CD9

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD9 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Mass Spectrometry (MS)

克隆位点

MEM-61
  • 原理

    Anti-Hu CD9 Purified

    特异性

    The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Pre-B cell line NALM-6.

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Western blotting: Recommended dilution: 2-4 μg/mL, non-reducing conditions.
    Immunohistochemistry (paraffin sections): Recommended dilution: 20 μg/mL, positive tissue: prostate.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Lafleur, Xu, Hemler: "Tetraspanin proteins regulate membrane type-1 matrix metalloproteinase-dependent pericellular proteolysis." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 2030-40, (2009) (PubMed).

    Singh, Sugimoto, Dhawan, Harris: "Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance." in: American journal of physiology. Cell physiology, Vol. 293, Issue 5, pp. C1660-8, (2007) (PubMed).

    Stöckl, Majdic, Fischer, Maurer, Knapp: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, (2001) (PubMed).

  • 抗原

    CD9

    别名

    CD9

    背景

    CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, BA2

    基因ID

    928

    UniProt

    P21926

    途径

    Response to Water Deprivation, Cell-Cell Junction Organization
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