CD72 抗体
(1 reference)Quick Overview for CD72 抗体 (ABIN94227)
抗原
See all CD72 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD72 Purified
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特异性
- The mouse monoclonal antibody 3F3 recognizes an extracellular epitope of CD72, a 39-43 kDa type II membrane glycoprotein (C-type lectin family). CD72 is a pan-B cell marker expressed throughout the B lymphocytes diferentiation with the exception of plasma cells, it is also present on follicular dendritic cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Normal human lymphocytes from a lymph node.
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亚型
- IgG2b
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anti-CD72 Molecule (CD72) (AA 117-359) antibody
CD72 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4G4B1 unconjugated
anti-CD72 Molecule (CD72) (AA 117-359) antibodyCD72 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2F3B8 unconjugated
anti-CD72 Molecule (CD72) (AA 169-359) antibodyCD72 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 143-345) antibodyCD72 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 126-237) antibodyCD72 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) antibodyCD72 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal BU40 unconjugated
anti-CD72 Molecule (CD72) (AA 4-110) antibodyCD72 适用: 人 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 150-208) antibodyCD72 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) antibodyCD72 适用: 人 WB, FACS, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal Bu40 unconjugated
anti-CD72 Molecule (CD72) (AA 117-226) antibodyCD72 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D10 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." in: PLoS ONE, Vol. 2, Issue 9, pp. e818, (2007) (PubMed).
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: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." in: PLoS ONE, Vol. 2, Issue 9, pp. e818, (2007) (PubMed).
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- CD72 (CD72 Molecule (CD72))
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别名
- CD72
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背景
- CD72 Molecule,CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.,LYB2
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基因ID
- 971
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UniProt
- P21854
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途径
- BCR Signaling
抗原
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