电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CD56 抗体

This anti-CD56 antibody is a 小鼠 单克隆 antibody detecting CD56 in FACS, IP, IHC (p) 和 ICC. Suitable for 人 和 Non-Human Primate. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN94187
发货至: 中国

Quick Overview for CD56 抗体 (ABIN94187)

抗原

See all CD56 (NCAM1) 抗体
CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

适用

  • 273
  • 73
  • 70
  • 24
  • 19
  • 12
  • 10
  • 9
  • 8
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
人, Non-Human Primate

宿主

  • 169
  • 106
  • 4
  • 1
  • 1
小鼠

克隆类型

  • 188
  • 87
  • 4
  • 2
单克隆

标记

  • 116
  • 15
  • 11
  • 10
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD56 antibody is un-conjugated

应用范围

  • 155
  • 141
  • 65
  • 62
  • 54
  • 43
  • 31
  • 31
  • 30
  • 30
  • 27
  • 15
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

克隆位点

MEM-188
  • 原理

    Anti-Hu CD56 Purified

    特异性

    The antibody MEM-188 reacts with an extracellular epitope on a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.

    交叉反应 (详细)

    Human, Non-Human Primates

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    KG-1 human acute myelogenous leukemia cell line

    亚型

    IgG2a
  • 应用备注

    Flow cytometry: Recommended dilution: 3 μg/mL. Immunohistochemistry (paraffin sections): Recommended dilution: 1:50, pretreatment: heat retrieval (microwave oven) in citrate buffer, standard ABC visualization, positive tissue: membrane-specific reaction in adjacent peripheral nerve, staining of paraprostatic autonomic ganglion.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Hovden, Karlsen, Jonsson, Aarstad, Appel: "Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses." in: BMC immunology, Vol. 12, pp. 2, (2011) (PubMed).

    Olsen, Tollefsen, Aagaard, Reitan, Bannantine, Andersen, Sollid, Lundin: "Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients." in: PLoS ONE, Vol. 4, Issue 5, pp. e5641, (2009) (PubMed).

    Drbal, Moertelmaier, Holzhauser, Muhammad, Fuertbauer, Howorka, Hinterberger, Stockinger, Schütz: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, (2007) (PubMed).

    Yates, Rovis, Mitchell, Afzali, Tsang, Garin, Lechler, Lombardi, Garden: "The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro." in: International immunology, Vol. 19, Issue 6, pp. 785-99, (2007) (PubMed).

  • 抗原

    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

    别名

    CD56

    背景

    Neural cell adhesion molecule 1,CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.,NCAM1, MSK39

    基因ID

    4684

    UniProt

    P13591
You are here:
Chat with us!