CD48 抗体
(5 references)Quick Overview for CD48 抗体 (ABIN94157)
抗原
See all CD48 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD48 Purified
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特异性
- The antibody MEM-102 reacts with CD48 (Blast-1), a 40-47 kDa GPI-anchored extracellular membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells, it is negative on granulocytes, platelets and erythrocytes.
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交叉反应 （详细）
- Human, Non-Human Primates
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Raji human Burkitt's lymphoma cell line
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亚型
- IgG1
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anti-CD48 (CD48) antibody (Biotin)
CD48 适用: 人, Non-Human Primate FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-102 Biotin
anti-CD48 (CD48) (AA 27-220) antibodyCD48 适用: 人 FACS, WB, ELISA, IF 宿主: 小鼠 Monoclonal 6F9H2 unconjugated
anti-CD48 (CD48) antibody (FITC)CD48 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-102 FITC
anti-CD48 (CD48) antibodyCD48 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-CD48 (CD48) (AA 1-243) antibodyCD48 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD48 (CD48) (AA 1-169) antibodyCD48 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B8-2C2 unconjugated
anti-CD48 (CD48) (AA 27-220) antibodyCD48 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM43 unconjugated Recombinant Antibody
anti-CD48 (CD48) antibody (PE)CD48 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-102 PE
anti-CD48 (CD48) antibody (APC)CD48 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-102 APC
anti-CD48 (CD48) (AA 47-181) antibodyCD48 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3F5H10 unconjugated
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应用备注
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Flow cytometry: Recommended dilution: 2 μg/mL.
Immunohistochemistry: Recommended dilution: 5-10 μg/mL. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).
: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, (2007) (PubMed).
: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).
: "Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19242-7, (1997) (PubMed).
: "Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102." in: Folia biologica, Vol. 35, Issue 5, pp. 289-97, (1990) (PubMed).
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: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).
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- CD48
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别名
- CD48
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背景
- CD48 Molecule,CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.,BCM1, BLAST, BLAST1, SLAMF2
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基因ID
- 962
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UniProt
- P09326
抗原
-
