CD45RA 抗体
(1 reference)Quick Overview for CD45RA 抗体 (ABIN94136)
抗原
See all CD45RA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD45RA Purified
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特异性
- The antibody MEM-56 reacts with an extracellular epitope of CD45RA, a 205-220 kDa single chain type I glycoprotein, variant of CD45 (CD45RA isoform). CD45RA is expressed on most of B lymphocytes, resting and native T lymphocytes, medullar thymocytes and monocytes.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human thymocytes and T lymphocytes.
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亚型
- IgG2b
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anti-CD45RA (CD45RA) antibody (PE)
CD45RA 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-56 PE
anti-CD45RA (CD45RA) antibodyCD45RA 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-472M unconjugated
anti-CD45RA (CD45RA) antibody (FITC)CD45RA 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-56 FITC
anti-CD45RA (CD45RA) antibody (APC)CD45RA 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-56 APC
anti-CD45RA (CD45RA) antibodyGMP Grade CD45RA 适用: 人 FACS 宿主: 小鼠 Monoclonal OTH-74D4 unconjugated
anti-CD45RA (CD45RA) antibody (FITC)CD45RA 适用: 人 FACS, IHC, IHC (p), IP, IHC (fro) 宿主: 小鼠 Monoclonal FITC
anti-CD45RA (CD45RA) antibodyCD45RA 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal B-C15 unconjugated
anti-CD45RA (CD45RA) antibody (Biotin)CD45RA 适用: 人 FACS, IHC (p), WB, IP 宿主: 小鼠 Monoclonal MEM-56 Biotin
anti-CD45RA (CD45RA) antibody (PerCP)CD45RA 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-56 PerCP
anti-CD45RA (CD45RA) antibody (FITC)CD45RA 适用: 人 FACS, IF, IHC (p), WB 宿主: 小鼠 Monoclonal 4AHI100 FITC
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应用备注
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Immunohistochemistry (paraffin sections): No pre-treatment of tissue sections is needed.
Flow cytometry: Recommended dilution: 0.3-4 μg/mL. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102." in: Folia biologica, Vol. 35, Issue 5, pp. 289-97, (1990) (PubMed).
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: "Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102." in: Folia biologica, Vol. 35, Issue 5, pp. 289-97, (1990) (PubMed).
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- CD45RA
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别名
- CD45RA
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背景
- CD45RA is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on naïve T cells and normal plasma cells.,PTPRCR, T200RA
抗原
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