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Integrin Alpha2b 抗体

Cited in 1 publication. This 小鼠 单克隆 anti-Integrin Alpha2b antibody (Clone HIP2) specifically detects Integrin Alpha2b in FACS 和 IHC (fro). The antibody is reactive with 人 和 Non-Human Primate samples.
产品编号 ABIN94112
发货至: 中国
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Quick Overview for Integrin Alpha2b 抗体 (ABIN94112)

抗原

See all Integrin Alpha2b (CD41) 抗体
Integrin Alpha2b (CD41)

适用

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人, Non-Human Primate

宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin Alpha2b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

HIP2
  • 原理

    Anti-Hu CD41b Purified

    特异性

    The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

    交叉反应 (详细)

    Human, Non-Human Primates

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    亚型

    IgG3
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Wu: "[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).

  • 抗原

    Integrin Alpha2b (CD41)

    别名

    CD41b

    背景

    Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,GT, GTA, GP2B, HPA3, GPIIb

    基因ID

    3674

    UniProt

    P08514

    途径

    Integrin Complex
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