Integrin Alpha2b 抗体
(1 reference)Quick Overview for Integrin Alpha2b 抗体 (ABIN94111)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD41a Purified
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特异性
- The antibody HIP8 reacts with an extracellular epitope on alpha (a) subunit of CD41 (heavy chain, 120 kDa). CD41 is mainly expressed on platelets and megakaryocytes. The antibody HIP8 blocks platelet aggregation and completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. HIP8 is useful in the morphological and physiological studies o platelets and megakaryocytes.
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交叉反应 （详细）
- Human, Non-Human Primates
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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亚型
- IgG1
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 适用: 人, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 小鼠 FACS, ELISA, IP, IHC (fro), IHC (p), Func 宿主: 大鼠 Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 小鼠 FACS, ELISA, IP, IHC (fro), IHC (p) 宿主: 大鼠 Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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: "[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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- Integrin Alpha2b (CD41)
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背景
- Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,GT, GTA, GP2B, HPA3, GPIIb
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基因ID
- 3674
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UniProt
- P08514
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途径
- Integrin Complex
抗原
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