CD2 抗体
(2 references)Quick Overview for CD2 抗体 (ABIN94021)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD2 Purified
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特异性
- The antibody MEM-65 recognizes a unique extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human peripheral T cells.
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亚型
- IgG1
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anti-CD2 (CD2) (AA 25-140) antibody
CD2 适用: 小鼠 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (N-Term) antibodyCD2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人 FACS, IF, WB, Func 宿主: 小鼠 Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 FITC
anti-CD2 (CD2) antibody (PE)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 PE
anti-CD2 (CD2) antibody (FITC)GMP Grade CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal OKT11 FITC
anti-CD2 (CD2) (AA 25-209) antibodyCD2 适用: 人 IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人, Pig, Non-Human Primate FACS, IF 宿主: 小鼠 Monoclonal LFA2-600 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
: "New monoclonal antibodies to human leucocyte surface molecule CD2." in: Folia biologica, Vol. 43, Issue 6, pp. 245-6, (1998) (PubMed).
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
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- CD2
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别名
- CD2
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背景
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
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基因ID
- 914
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UniProt
- P06729
抗原
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