beta-2 Microglobulin 抗体 (Biotin)
(4 references)Quick Overview for beta-2 Microglobulin 抗体 (Biotin) (ABIN93904)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu beta2-Microglobulin Biotin
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特异性
- The mouse monoclonal antibody B2M-01 reacts with beta2-microglobulin (beta2M, extracellular antigen), associated with cell-surface MHC Class I molecules and other membrane antigens, as well as it reacts with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
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无交叉反应
- 小鸡, Cow, 犬, 小鼠, 兔
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
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免疫原
- Purified human beta2-microglobulin
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亚型
- IgG2a
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anti-beta-2-Microglobulin (B2M) (AA 1-119) antibody
B2M 适用: 人 WB, ELISA, IF, IHC (p), RNAi, PLA 宿主: 小鼠 Monoclonal 3F9-2C2 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 21-100) antibodyB2M 适用: 人 WB, FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3G5H8 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 22-119) antibodyB2M 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A2 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 22-119) antibodyB2M 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal rB2M-961 unconjugated Recombinant Antibody
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate WB, FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal B2M-961 unconjugated
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate IHC, StM 宿主: 小鼠 Monoclonal B2M-1118 unconjugated
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人 WB, FACS, ELISA, IP, ICC, IHC (p), RIA 宿主: 小鼠 Monoclonal B2M-01 unconjugated
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal B2M-961 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 22-119) antibodyB2M 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
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应用备注
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Flow cytometry: Recommended dilution: 1-2 μg/mL, positive control: peripheral blood lymphocytes, negative control: DAUDI human Burkitt lymphoma cell line, erythrocytes.
Western blotting: Recommended dilution: 2 μg/mL, non-reducing conditions. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "HLA-G5 in the blood of leukemia patients and healthy individuals." in: Leukemia research, Vol. 37, Issue 2, pp. 139-45, (2013) (PubMed).
: "Urine proteomic profiling of pediatric nephrotic syndrome." in: Pediatric nephrology (Berlin, Germany), Vol. 21, Issue 9, pp. 1257-65, (2006) (PubMed).
: "Modulation of HLA-G expression in human neural cells after neurotropic viral infections." in: Journal of virology, Vol. 79, Issue 24, pp. 15226-37, (2005) (PubMed).
: "The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin." in: Folia biologica, Vol. 30, Issue 6, pp. 369-76, (1985) (PubMed).
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: "HLA-G5 in the blood of leukemia patients and healthy individuals." in: Leukemia research, Vol. 37, Issue 2, pp. 139-45, (2013) (PubMed).
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- beta2-Microglobulin
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背景
- Beta-2-microglobulin,Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.,B2M
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基因ID
- 567
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UniProt
- P61769
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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