Nef 抗体 (FITC)
This anti- antibody is a 小鼠 单克隆 antibody detecting in WB 和 ELISA. Suitable for Human Immunodeficiency Virus (HIV).
Quick Overview for Nef 抗体 (FITC) (ABIN933664)
抗原
Nef
适用
Human Immunodeficiency Virus (HIV)
宿主
小鼠
克隆类型
单克隆
标记
FITC
应用范围
Western Blotting (WB), ELISA
克隆位点
2H12 N-terminus
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交叉反应 （详细）
- Reacts with recombinant nef in ELISA and WB.
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纯度
- > 95 % pure
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免疫原
- HIV1 Nef antibody (FITC) was raised using purified recombinant nef (HIV-1) produced in E.coli expression system as the immunogen.
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亚型
- IgG1
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anti-Nef (AA 1-209) antibody
适用: Human Immunodeficiency Virus (HIV) WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1:1,000, WB: 1:1,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Supplied lyophilized in PBS buffer.
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注意事项
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Avoid repeated freeze/thaw cycles.
Product is photosensitive and should be protected from light.
Dilute only prior to immediate use. -
储存条件
- -80 °C
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储存方法
- Aliquot and store at -70 °C or lower.
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- Nef
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物质类
- Viral Protein
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背景
- Nef is a early protein that may play a role in optimizing the host cell environment for viral replication without causing apoptosis. Nef enhances virus infectivity and pathogenicity. It down regulates surface MHC I molecules and internalized molecules are sequestered to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. . Synonyms: Monoclonal HIV1 Nef antibody, Anti-HIV1 Nef antibody, HIV-1 Nef antibody, 3'ORF antibody, ABIN antibody, ABIN1 antibody,C terminal core protein antibody, F protein antibody, Nef antibody, Negative factor antibody, p27 antibody, VAN antibody.
抗原
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