SMAD1 抗体
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北京 101111
Quick Overview for SMAD1 抗体 (ABIN933125)
抗原
See all SMAD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not studied.
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纯化方法
- Protein G affinity chromatography
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免疫原
- SMAD1 antibody was raised in mouse using recombinant Human Smad Family Member 1 (Smad1)
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亚型
- IgG1
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应用备注
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WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- SMAD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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别名
- SMAD1
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背景
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. Synonyms: Monoclonal SMAD1 antibody, Anti-SMAD1 antibody, Transforming growth factor beta signaling protein 1 antibody, BSP1 antibody, JV41 antibody, JV4-1 antibody, MADH1 antibody, MADR1 antibody.
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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