SNCA 抗体
Our Local Distributor
北京 101111
Quick Overview for SNCA 抗体 (ABIN932750)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
免疫原
- alpha Synuclein antibody was raised in Mouse using a purified recombinant fragment of SNCA expressed in E. coli as the immunogen.
-
-
-
-
应用备注
-
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
-
-
- SNCA (Synuclein, alpha (SNCA))
-
别名
- alpha Synuclein
-
背景
- SNCA belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy. Synonyms: Monoclonal Synuclein Alpha antibody, Anti-Synuclein Alpha antibody, MGC110988 antibody, NACP antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, Non A4 Component Of Amyloid Precursor antibody, SNCA antibody.
-
途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-